UC LEADS Scholar · UCSD Researcher

Fabrizio Malatesta

Undergraduate Researcher · Bioinformatics & Computational Genomics

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01 / About
B.S. Biology · Bioinformatics Specialization · CS Minor

University of California, San Diego

I am a Bioinformatics student at UC San Diego with a deep interest in the intersection of biological data and computational modeling. My academic foundation combines a major in Biology (Specialization in Bioinformatics) with a minor in Computer Science, providing me with the interdisciplinary toolkit necessary to tackle complex genomic questions. I am particularly passionate about:

  • Computational Genomics & Statistical Genetics: Leveraging large-scale data to understand disease mechanisms.
  • Algorithmic Development: Applying data structures and runtime analysis to biological pipelines.
  • Interdisciplinary Research: Bridging the gap between “wet lab” biological questions and “dry lab” computational solutions.

I am also a UC LEADS Scholar, actively preparing to pursue a Ph.D. to further explore the potential of Bioinformatics in improving human health. When I'm not in the lab or at the computer, you can usually find me rock climbing, training Muay Thai, or following the latest in soccer.

3.8

GPA

Provost Honors

2027

Expected Grad.

02 / Research & Experience

Research Timeline

Sanchez-Roige Lab — UCSD

La Jolla, CA

Research InternFall 2025 – Present
  • Leading a project analyzing the genetic architecture of wisdom using GWAS and population-level genomic analyses.
  • Implementing various tools across different platforms for multi-variate genetic analysis.

Presentations

URC 2026 @ UCSDMURALS 2026 @ UCSD

McVicker Lab — Salk Institute

La Jolla, CA

Research InternSummer 2025
  • Designed and implemented a computational framework in Bash and Python to identify low-frequency off-target genome edits from Superb-seq single-cell sequencing data.
  • Aimed to distinguish off-target Cas9-mediated events from spontaneous breaks or technical artifacts.

Presentations

NCRC 2026 @ HarvardNCUR 2026 @ RichmondSRC 2025 @ UCSDUC LEADS Symposium 2026 @ UCSF

Mueller Lab — Salk Institute

La Jolla, CA

Lab Tech IFall 2024 – Summer 2025
  • Conducted experiments on arbuscular mycorrhiza symbiosis using PCR, gel electrophoresis, spore inoculation, microscopy analysis, and gene extraction.
  • Designed an independent peptide treatment study across multiple plant species and presented findings to the lab.

Weill Cornell Medicine

New York, NY

Research AssistantSummer 2022
  • Conducted experiments on mitochondrial myopathies in mice to test potential therapeutic approaches.

Mediakite

New York, NY

Production Crew Member2019 – 2023
  • Managed tasks at on-location shoots including set construction, camera work, and facilitating clear communication between staff and clients.

Alliance NY Team — Compass Real Estate

New York, NY

Assistant2023
  • Assisted with creating and updating property listings, showings, and effective client communications.
03 / Leadership & Activities

Beyond the Lab Bench

Competitive Fellowship

UC LEADS Scholar

University of California

Selected as one of a limited number of scholars for this UC-wide research and leadership program. This fellowship supports my Ph.D. pursuits for a TBD number of years within the UC system.

2025 – 2027
Executive Role

Finance Chair

Undergraduate Bioinformatics Club (UBIC)

Managed event finances and logistics, directly enabling bioinformatics student body engagement and activities across the department.

2025 – 2026
Leadership

Secretary

Tau Kappa Epsilon — UCSD Chapter

Coordinated meetings and events for an 80-member organization. Managed funding logistics and organized philanthropic events raising thousands of dollars for St. Jude Children's Research Hospital.

2024 – 2025
Advocacy

Student Representative

BICD 100 (Genetics)

Participated in weekly faculty meetings to represent student feedback and share class-wide updates, bridging communication between students and instructors.

Fall 2024
Mentorship

Mentor Collective Program

UC San Diego

Served as a mentor for an incoming freshman, providing guidance and support during their transition to university life.

2025 – 2026
Fellowship

Triton Research & Experiential Learning Scholar

TRELS — UC San Diego

A program empowering students to pursue intellectual opportunities beyond the classroom through funding and mentorship support.

Winter 2026
04 / Skills

Toolkit & Expertise

Technical

PythonJavaBashC++LaTeXFIJI / ImageJMicrosoft OfficePADI Advanced Open Water

Research

Genomic data analysisStatistical GeneticsGenomic Data VisualizationMolecular techniquesExperimental designData interpretationGWASLDSCGenomicSEM

Communication

Scientific presentationsPublic speakingMentoringCollaborative teamwork

Languages

English (Fluent)Italian (Fluent)Spanish (Proficient)
06 / Academic Media

Posters & Abstracts

Abstract

Identifying Low-Frequency Off-Target Genome Edits from Superb-seq Data

McVicker Lab — Salk Institute · 2025

View
Poster

Identifying Low-Frequency Off-Target Genome Edits from Superb-seq Data

NCRC 2026 @ Harvard · 2026

View
Poster

Identifying Low-Frequency Off-Target Genome Edits from Superb-seq Data

UC LEADS Symposium 2026 @ UCSF · 2026

View
Abstract

Genetic Architecture of Wisdom: A Multi-Variate Genomic Analysis

Sanchez-Roige Lab — UC San Diego · 2026

Coming soon
Poster

Genetic Architecture of Wisdom: A Multi-Variate Genomic Analysis

Sanchez-Roige Lab — UC San Diego · 2026

Coming soon
07 / Résumé

Curriculum Vitae

fabrizio-malatesta-resume.pdf

View My Résumé

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